WHAT IS REGENERATIVE MEDICINE?
Regenerative medicine is a new therapeutic approach aimed at biological tissue regeneration rather than replace it.
WHAT ARE THE CELL CONCENTRATED?
They contain a number of important growth factors that stimulate certain cellular mechanisms related to tissue growth: Angiogenesis, Chemotaxis of macrophages, Fibroblast proliferation and migration, Collagen synthesis.
WHAT ARE THE STEM CELLS?
Differentiation of Mesenchymal Cells: Osteoblasts – Bone.
Differentiation of Stem cells: Chondrocytes – Cartilage – Fibroblasts – Connective Tissue – Tendons – Ligaments – Myocytes – Muscle.
Exert during the process of tissue damage was leaving, all their functions:
hemostasis,capillary maintenance of identity, phagocytosis, active transport, repair and healing.
THE GROWTH FACTORS
The GFs are numerous and each one performs a specific function:
PDGF (Platelet Derived Growth Factor) stimulates cell replication (mitogenesis), the differentiation, the replication of endothelial cells and angiogenesis.
EGF (Epidermal Growth Factor) is responsible for cell differentiation and stimulates re-epithelialization, angiogenesis and the activity of collagen.
IGF (Insulin Growth Factor) important in wound healing and stimulates the proliferation and the different functions of osteoblasts.
VEGF (Vascular Endotelium Growth Factor) involved in processes such as inflammation, angiogenesis of ischemic cells. It induces an increase in the permeability of blood capillaries.
FGF (Fibroblast Growth Factor) of fibroblast growth factor.
TGF (Transforming Growth Factor) regulate the proliferation and differentiation of cell lines: osteoblasts, fibroblasts, endothelial cells and stem cells.
TECHNOLOGY FOR PREPARATION OF AUTOLOGOUS CELL CONCENTRATED IN ADVANCED REGENERATIVE CELLULAR THERAPIES
Release of growth factors from Leukocytes and Thrombocytes.
Chemo-tactic actionand cell migration.
Mitosis and cell proliferation.
Cell Concentrates are used for the purpose of biostimulation in all those pathologies of loss of substance.
Their application creates a bio-repair effect determined by an acceleration of the patient’s cell proliferation.